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>新着情報 >24 25 The vaccine was presented as an aluminium hydroxide
24 25 The vaccine was presented as an aluminium hydroxide

Indeed, Milich et al showed that in mice the independent genetic regulation of immune responses to pre S1, pre S2, and S regions of hepatitis B surface antigen that are linked to the major histocompatibility complex would assure fewer genetic non responders to a vaccine containing all three antigenic regions. The vaccine is a third generation vaccine containing pre S1, pre S2, and S antigenic components of both viral surface antigen subtypes adw and ayw. All three antigenic components are produced in a continuous mammalian cell line, the mouse c127 clonal cell line, after transfection of the cells with recombinant hepatitis B surface antigen DNA.24 25 The vaccine was presented as an aluminium hydroxide adjuvant preparation of purified antigenic proteins in 1.0 ml of isotonic saline..

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